Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 20/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26059141 | 1.00 | OPRL1 (0.36) | OPRL1 | |
| SCHEMBL31387422 | 0.89 | JAK2 (0.36) | OPRL1 | |
| SCHEMBL26066260 | 0.89 | JAK2 (0.36) | OPRL1 | |
| SCHEMBL26066409 | 0.89 | JAK2 (0.36) | OPRL1 | |
| SCHEMBL31387369 | 0.89 | JAK2 (0.36) | OPRL1 | |
| SCHEMBL25357190 | 0.88 | OPRL1 (0.40) | OPRL1 | |
| SCHEMBL25355295 | 0.88 | OPRL1 (0.40) | OPRL1 | |
| SCHEMBL30623268 | 0.88 | JAK2 (0.35) | OPRL1 | |
| SCHEMBL31387456 | 0.88 | JAK2 (0.35) | OPRL1 | |
| SCHEMBL26066279 | 0.88 | JAK2 (0.35) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119343353-A | 2-Methyl-4 ',5' -dihydrospiro [ piperidine-4, 7' -thieno [2,3-c ] pyran ] derivatives as APOL1 inhibitors and methods of use thereof | 弗特克斯药品有限公司 | 2025-01-21 | — | — | CN | disclosed |