⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26064356 | 1.00 | — | — | |
| SCHEMBL25359359 | 0.88 | — | — | |
| SCHEMBL26066138 | 0.88 | JAK2 (0.30) | — | |
| SCHEMBL26062286 | 0.88 | JAK2 (0.30) | — | |
| SCHEMBL31387257 | 0.88 | JAK2 (0.30) | — | |
| SCHEMBL26062295 | 0.88 | JAK2 (0.30) | — | |
| SCHEMBL31387325 | 0.88 | JAK2 (0.30) | — | |
| SCHEMBL29413758 | 0.87 | — | — | |
| SCHEMBL24345802 | 0.87 | — | — | |
| SCHEMBL25360469 | 0.87 | ADORA1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119343353-A | 2-Methyl-4 ',5' -dihydrospiro [ piperidine-4, 7' -thieno [2,3-c ] pyran ] derivatives as APOL1 inhibitors and methods of use thereof | 弗特克斯药品有限公司 | 2025-01-21 | — | — | CN | disclosed |