Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | PDE1A | P54750 | 1/20 | 0.44 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 5/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 5/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 9/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31496868 | 0.80 | ADORA1 (0.43) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL31496948 | 0.76 | ADORA1 (0.41) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL31496922 | 0.73 | ADORA1 (0.41) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL31496927 | 0.73 | ADORA1 (0.43) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL23087910 | 0.72 | ADORA1 (0.53) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL30753025 | 0.72 | PRMT5 (0.47) | PRMT5WDR77PARP1 | |
| SCHEMBL30752953 | 0.72 | PARP1 (0.41) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL30752986 | 0.70 | ADORA1 (0.43) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL23087259 | 0.70 | ADORA1 (0.44) | ADORA1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL23087512 | 0.70 | ADORA1 (0.44) | ADORA1PDE1APDE1BPDE3BPDE1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119490500-A | PRMT5 inhibitor, preparation method and application thereof | 上海艾力斯医药科技股份有限公司 | 2025-02-21 | — | — | CN | disclosed |