SCHEMBL31388186

CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CS)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccccc1)C(C)C)C(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CS)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)O)[C@@H](C)O)[C@@H](C)O)C(C)C

nearest known ligand 0.69

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	CALCR	P30988	6/20	0.69

▸	F2	P00734	4/20	0.66

▸	CRHR1	P34998	1/20	0.62

▸	CRHR2	Q13324	1/20	0.62

▸	HCRTR1	O43613	1/20	0.61

▸	HCRTR2	O43614	1/20	0.61

▸	GLP1R	P43220	5/20	0.60

▸	CCKBR	P32239	2/20	0.60

▸	GCGR	P47871	3/20	0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29361541	0.93	CALCR (0.70)	CALCRGLP1RGCGR
SCHEMBL30432714	0.92	CALCR (0.67)	CALCRF2CRHR1CRHR2HCRTR1
SCHEMBL31167610	0.91	CALCR (0.71)	CALCRF2GLP1RGCGR
SCHEMBL30752380	0.91	CALCR (0.71)	CALCRF2GLP1RGCGR
SCHEMBL30752384	0.91	CALCR (0.71)	CALCRGLP1RGCGR
SCHEMBL30607425	0.90	CALCR (0.66)	CALCRF2CRHR1CRHR2HCRTR1
SCHEMBL30752386	0.90	CALCR (0.69)	CALCRF2GLP1RGCGR
SCHEMBL30752383	0.90	CALCR (0.70)	CALCRHCRTR1HCRTR2GLP1RGCGR
SCHEMBL30432219	0.89	CALCR (0.62)	CALCRF2CRHR1CRHR2HCRTR1
SCHEMBL30746744	0.89	CALCR (0.58)	CALCRF2CRHR1CRHR2GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-119161447-A	Long-acting insulin analogue, and preparation method and application thereof	濮阳市旌胜新能源科技有限公司	2024-12-20	—	—	CN	disclosed