SCHEMBL31388239

SCHEMBL31388239

Clc1ccc(C(CC2CCCC2)c2ccncc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.50
SLC6A2 P23975 3/20 0.48
SLC6A4 P31645 3/20 0.48
SLC6A3 Q01959 3/20 0.48
AKT1 P31749 3/20 0.48
PDE4A P27815 8/20 0.44
GCK P35557 1/20 0.39
PRCP P42785 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
FFAR2 O15552 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31388237 0.84 PDE4A (0.44) CYP19A1PDE4AGCKPRCPCYP2C9
SCHEMBL31388228 0.84 GCK (0.53) CYP19A1SLC6A2SLC6A4SLC6A3PDE4A
SCHEMBL31388243 0.83 PDE4A (0.39) CYP19A1AKT1PDE4AGCK
SCHEMBL31388235 0.80 CYP17A1 (0.56) CYP19A1SLC6A2SLC6A4SLC6A3PDE4A
SCHEMBL29706730 0.75 SLC6A2 (0.54) SLC6A2SLC6A4SLC6A3
SCHEMBL31388238 0.74 TSHR (0.37) SLC6A2SLC6A4SLC6A3PDE4AGCK
SCHEMBL29706727 0.73 GAA (0.47) CYP19A1GCKCYP1A2CYP2D6
SCHEMBL31388227 0.72 GCK (0.38) CYP19A1SLC6A2SLC6A4SLC6A3GCK
SCHEMBL10633563 0.71 SLC6A2 (0.54) SLC6A2SLC6A4SLC6A3CYP3A4
SCHEMBL8247864 0.71 SLC6A2 (0.51) SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431348-B Preparation method and application of pyridine derivative compound 浙江理工大学 2026-05-12 CN disclosed
CN-119431348-A Preparation method and application of pyridine derivative compound 浙江理工大学 2025-02-14 CN disclosed