Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 20/20 | 0.57 |
| ▸ | GSPT1 | P15170 | 7/20 | 0.57 |
| ▸ | DDB1 | Q16531 | 5/20 | 0.57 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21069987 | 0.93 | CRBN (0.66) | CRBNGSPT1DDB1IKZF3CYP2C19 | |
| SCHEMBL30484237 | 0.91 | CRBN (0.59) | CRBNGSPT1DDB1IKZF3CYP2C19 | |
| SCHEMBL26132598 | 0.91 | CRBN (0.61) | CRBNGSPT1DDB1IKZF3CYP2C19 | |
| SCHEMBL30484280 | 0.91 | CRBN (0.61) | CRBNGSPT1DDB1IKZF3CYP2C19 | |
| SCHEMBL23240043 | 0.89 | CRBN (0.59) | CRBNGSPT1DDB1IKZF3CYP2C19 | |
| SCHEMBL29716247 | 0.89 | CRBN (0.59) | CRBNGSPT1DDB1IKZF3CYP2C19 | |
| SCHEMBL29368466 | 0.88 | CRBN (0.60) | CRBNGSPT1DDB1IKZF3CYP2C19 | |
| SCHEMBL26474240 | 0.88 | CRBN (0.58) | CRBNGSPT1DDB1IKZF3CYP2C19 | |
| SCHEMBL26471891 | 0.87 | CRBN (0.48) | CRBNGSPT1DDB1IKZF3CYP2C19 | |
| SCHEMBL23240144 | 0.87 | CRBN (0.59) | CRBNGSPT1DDB1IKZF3CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |