Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.68 |
| ▸ | DDB1 | Q16531 | 9/20 | 0.49 |
| ▸ | AR | P10275 | 4/20 | 0.49 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31390660 | 1.00 | CRBN (0.68) | CRBNDDB1ARALKALDH1A1 | |
| SCHEMBL29927364 | 0.94 | CRBN (0.67) | CRBNDDB1ARALKALDH1A1 | |
| SCHEMBL26495659 | 0.94 | CRBN (0.67) | CRBNDDB1ARALKALDH1A1 | |
| SCHEMBL29132171 | 0.94 | CRBN (0.67) | CRBNDDB1ARALKALDH1A1 | |
| SCHEMBL20234536 | 0.94 | CRBN (0.67) | CRBNDDB1ARALKALDH1A1 | |
| SCHEMBL29927679 | 0.92 | CRBN (0.71) | CRBNDDB1ARALKALDH1A1 | |
| SCHEMBL20231272 | 0.92 | CRBN (0.71) | CRBNDDB1ARALKALDH1A1 | |
| SCHEMBL29132341 | 0.91 | CRBN (0.65) | CRBNDDB1ARALKALDH1A1 | |
| SCHEMBL29132298 | 0.91 | CRBN (0.65) | CRBNDDB1ARALKALDH1A1 | |
| SCHEMBL29927985 | 0.91 | CRBN (0.65) | CRBNDDB1ARALKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504710-A | PROTACs compound for targeted degradation of PRMT5 and application thereof | 昆明医科大学 | 2025-02-25 | — | — | CN | disclosed |