SCHEMBL31395671

SCHEMBL31395671

[N-]=[N+]=NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ MGMT P16455 1/20 0.35
▸ ABCG2 Q9UNQ0 6/20 0.33
▸ BLM P54132 1/20 0.32
▸ PMP22 Q01453 1/20 0.32
▸ HSD17B10 Q99714 1/20 0.32
▸ CRBN Q96SW2 3/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.32
▸ TTR P02766 1/20 0.31
▸ LMNA P02545 1/20 0.31
▸ ALKBH5 Q6P6C2 1/20 0.31
▸ SUCNR1 Q9BXA5 1/20 0.31
▸ EGLN1 Q9GZT9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26016262 1.00 MGMT (0.35) MGMTABCG2BLMPMP22HSD17B10
SCHEMBL13658532 1.00 MGMT (0.35) MGMTABCG2BLMPMP22HSD17B10
SCHEMBL26692655 1.00 MGMT (0.35) MGMTABCG2BLMPMP22HSD17B10
SCHEMBL20383110 1.00 MGMT (0.35) MGMTABCG2BLMPMP22HSD17B10
SCHEMBL14713433 1.00 MGMT (0.35) MGMTABCG2BLMPMP22HSD17B10
SCHEMBL19581482 1.00 MGMT (0.35) MGMTABCG2BLMPMP22HSD17B10
SCHEMBL29649445 1.00 MGMT (0.35) MGMTABCG2BLMPMP22HSD17B10
SCHEMBL22444946 1.00 MGMT (0.35) MGMTABCG2BLMPMP22HSD17B10
SCHEMBL22690101 1.00 MGMT (0.35) MGMTABCG2BLMPMP22HSD17B10
SCHEMBL15669474 1.00 MGMT (0.35) MGMTABCG2BLMPMP22HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025031923-A1 IMIDAZO[4,5-D]PYRIDAZINE COMPOUNDS AND CONJUGATES THEREOF, THEIR PREPARATION, AND THEIR THERAPEUTIC APPLICATIONS SANOFI (FR) 2025-02-13 — — WO disclosed
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