Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL31395705

CCCCc1nc2c(N)nnc(OC(C)C)c2n1C[C@H]1CC[C@H](CN)CC1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 18/20 0.42
TLR8 Q9NR97 11/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31395430 0.91 TLR7 (0.46) TLR7TLR8
Hydrochloric Acid SCHEMBL31395700 0.90 TLR7 (0.46) TLR7TLR8
Hydrochloric Acid SCHEMBL29840829 0.90 TLR7 (0.46) TLR7TLR8
SCHEMBL29109811 0.84 TLR7 (0.46) TLR7TLR8
Hydrochloric Acid SCHEMBL29840857 0.82 TLR7 (0.56) TLR7TLR8
SCHEMBL29840836 0.81 TLR7 (0.46) TLR7TLR8
Trifluoroacetic Acid SCHEMBL29109922 0.81 TLR7 (0.53) TLR7TLR8
Trifluoroacetic Acid SCHEMBL29840804 0.81 TLR7 (0.53) TLR7TLR8
Trifluoroacetic Acid SCHEMBL29109862 0.79 TLR7 (0.52) TLR7TLR8
Trifluoroacetic Acid SCHEMBL29840701 0.79 TLR7 (0.52) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025031923-A1 IMIDAZO[4,5-D]PYRIDAZINE COMPOUNDS AND CONJUGATES THEREOF, THEIR PREPARATION, AND THEIR THERAPEUTIC APPLICATIONS SANOFI (FR) 2025-02-13 WO disclosed