Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.53 |
| ▸ | VCP | P55072 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 10/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.42 |
| ▸ | JAK1 | P23458 | 2/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31397951 | 0.89 | TYK2 (0.50) | NPC1RAB9ASMN1; SMN2NLRP3VCP | |
| SCHEMBL31397954 | 0.85 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2NLRP3VCP | |
| SCHEMBL31397976 | 0.84 | IRAK4 (0.54) | NPC1RAB9ASMN1; SMN2NLRP3JAK2 | |
| SCHEMBL31397929 | 0.84 | SMN1; SMN2 (0.45) | NPC1RAB9ASMN1; SMN2NLRP3VCP | |
| SCHEMBL31397965 | 0.82 | IRAK4 (0.45) | NPC1RAB9ASMN1; SMN2NLRP3VCP | |
| SCHEMBL31397946 | 0.81 | JAK2 (0.53) | JAK2IRAK4JAK1TYK2JAK3 | |
| SCHEMBL31397927 | 0.81 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2NLRP3VCP | |
| SCHEMBL31397930 | 0.80 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2NLRP3VCP | |
| SCHEMBL31398161 | 0.79 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2NLRP3JAK2 | |
| SCHEMBL31397988 | 0.76 | CDKN1A (0.44) | NPC1RAB9ASMN1; SMN2NLRP3VCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024262911-A1 | NOVEL PYRAZOLO PYRIMIDINE-BASED COMPOUND AND USE THEREOF | 주식회사 에이조스바이오 | 2024-12-26 | — | — | WO | disclosed |