SCHEMBL3140072

SCHEMBL3140072

Cc1cccc(C(=O)c2cc(C(=O)c3cccc(C)c3)c(O)cc2O)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.62
PARP1 P09874 1/20 0.53
CNR2 P34972 3/20 0.53
KMT2A Q03164 4/20 0.52
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
HDAC8 Q9BY41 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
CNR1 P21554 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
HPGD P15428 3/20 0.47
KDM4E B2RXH2 2/20 0.47
LMNA P02545 2/20 0.47
MAPT P10636 2/20 0.47
MEN1 O00255 2/20 0.47
HTT P42858 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
TP53 P04637 1/20 0.46
CYP3A4 P08684 1/20 0.46
RECQL P46063 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8088885 0.95 POLB (0.66) POLBPARP1CNR2KMT2ANPC1
SCHEMBL22500486 0.89 HSP90AA1 (0.54) POLBPARP1CNR2KMT2ANPC1
SCHEMBL5709932 0.84 KMT2A (0.67) POLBPARP1CNR2KMT2ANPC1
SCHEMBL30374826 0.84 KMT2A (0.67) POLBPARP1CNR2KMT2ANPC1
Bicarbonate SCHEMBL10798365 0.84 POLB (0.56) POLBPARP1CNR2KMT2ANPC1
SCHEMBL3132232 0.84 POLB (0.60) POLBPARP1CNR2KMT2ANPC1
SCHEMBL3357813 0.84 POLB (0.70) POLBPARP1CNR2KMT2ANPC1
SCHEMBL186545 0.82 PARP1 (0.68) POLBPARP1CNR2KMT2AHDAC8
SCHEMBL29503529 0.82 PARP1 (0.68) POLBPARP1CNR2KMT2AHDAC8
SCHEMBL7627304 0.82 HPGD (0.61) POLBCNR2KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010036295-A1 ULTRAVIOLET LIGHT STABILIZING COMPOUNDS AND ASSOCIATED MEDIA AND DEVICES GENTEX CORPORATION (US) 2010-04-01 WO disclosed
WO-2010036295-A1 ULTRAVIOLET LIGHT STABILIZING COMPOUNDS AND ASSOCIATED MEDIA AND DEVICES GENTEX CORPORATION (US) 2010-04-01 WO disclosed
US-20100073754-A1 Ultraviolet light stabilizing compounds and associated media and devices GENTEX CORPORATION 2010-03-25 US disclosed
US-20100073754-A1 Ultraviolet light stabilizing compounds and associated media and devices GENTEX CORPORATION 2010-03-25 US disclosed
US-20100073754-A1 Ultraviolet light stabilizing compounds and associated media and devices GENTEX CORPORATION 2010-03-25 US disclosed