⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL11166078 | 0.60 | — | — | |
| SCHEMBL6744529 | 0.56 | — | — | |
| SCHEMBL6369223 | 0.56 | — | — | |
| SCHEMBL6850309 | 0.56 | — | — | |
| SCHEMBL26005 | 0.54 | — | — | |
| SCHEMBL10978193 | 0.54 | — | — | |
| SCHEMBL222182 | 0.54 | — | — | |
| SCHEMBL2125267 | 0.54 | — | — | |
| SCHEMBL72745 | 0.54 | — | — | |
| SCHEMBL4420181 | 0.50 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 677 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024099135-A1 | 1,5-NAPHTHYRIDINE CGAS INHIBITOR AND USE THEREOF | 杭州中美华东制药有限公司 | 2024-05-16 | — | — | WO | claimed |
| EP-4251621-A1 | AROMATIC SPIRO RING AMIDE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | F. Hoffmann-La Roche AG (CH) | 2023-10-04 | — | — | EP | claimed |
| US-20230286969-A1 | AROMATIC SPIRO RING AMIDE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HOFFMANN-LA ROCHE INC. (US) | 2023-09-14 | — | — | US | claimed |
| CN-116390920-A | Aromatic spirocyclic amide derivatives for the treatment and prevention of hepatitis b virus infection | 豪夫迈·罗氏有限公司 | 2023-07-04 | — | — | CN | claimed |
| US-11591299-B1 | Prodrug compound of levosimendan, preparation method and use thereof | Beijing Chenguang Tongchuang Pharmaceutical Research Institute Co., Ltd. (CN) | 2023-02-28 | — | — | US | claimed |
| WO-2022112207-A1 | AROMATIC SPIRO RING AMIDE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2022-06-02 | — | — | WO | claimed |
| CN-111333552-B | Synthesis method of beta-benzo amino acid compound | 广州安岩仁医药科技有限公司 | 2021-07-20 | — | — | CN | claimed |
| CN-111333552-A | β -benzo amino acid compound synthesis method | 广州安岩仁医药科技有限公司 | 2020-06-26 | — | — | CN | claimed |
| CN-111285873-A | RET inhibitors, pharmaceutical compositions thereof and uses thereof | 广东东阳光药业有限公司 | 2020-06-16 | — | — | CN | claimed |
| EP-3436821-A2 | DETECTING MICROBIAL INFECTION IN WOUNDS | Synovo GmbH (DE) | 2019-02-06 | — | — | EP | claimed |
| WO-2000008041-A9 | STRUCTURAL ANALOGS OF AMINE BASES AND NUCLEOSIDES | BIO RAD LABORATORIES (US) | 2001-02-01 | — | — | WO | claimed |
| WO-2000008041-A1 | STRUCTURAL ANALOGS OF AMINE BASES AND NUCLEOSIDES | BIO-RAD LABORATORIES (US) | 2000-02-17 | — | — | WO | claimed |
| EP-0898575-A2 | A COMBINATORIAL PROTECTING GROUP STRATEGY FOR MULTIFUNCTIONAL MOLECULES | KÖSTER, Hubert (US) | 1999-03-03 | — | — | EP | claimed |
| WO-1997041139-A2 | A COMBINATORIAL PROTECTING GROUP STRATEGY FOR MULTIFUNCTIONAL MOLECULES | KOESTER HUBERT (US) | 1997-11-06 | — | — | WO | claimed |
| EP-0582261-A1 | Cephalosporin compounds and processes for the preparation thereof | LUCKY LTD. (KR) | 1994-02-09 | — | — | EP | claimed |
| EP-0280139-A2 | Complex copper formazane compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-31 | — | — | EP | claimed |
| EP-0050019-B1 | 3-KETO-4-(4'-AROMATICALLY SUBSTITUTED-PHENOXY) COMPOUNDS, THEIR 3- ALKYLATED ENOL AND 2,3-HYDROGENATED DERIVATIVES AND THE USE THEREOF FOR THE CONTROL OF WEEDS | SANDOZ AG (CH) | 1986-04-09 | — | — | EP | claimed |
| EP-0031959-B1 | METHOD FOR HARDENING PHOTOGRAPHIC GELATIN LAYERS | Agfa-Gevaert AG (DE) | 1983-03-30 | — | — | EP | claimed |
| EP-0001629-A1 | Water-soluble, fibre-reactive, green azo-phthalocyanine dyestuffs, their preparation and their use | CASSELLA Aktiengesellschaft (DE) | 1979-05-02 | — | — | EP | claimed |
| US-4087271-A | 1,2-Bis (thioalkyl) alkanes and derivatives thereof as abscission agents | THE PROCTER & GAMBLE COMPANY (US) | 1978-05-02 | — | — | US | claimed |