SCHEMBL31403629

SCHEMBL31403629

Nc1cnc(OC2CCC2)cn1

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FEN1 P39748 10/20 0.42
ALOX5AP P20292 9/20 0.42
PDGFRB P09619 2/20 0.41
PDGFRA P16234 2/20 0.41
PIM1 P11309 1/20 0.39
PIM3 Q86V86 1/20 0.39
PIM2 Q9P1W9 1/20 0.39
LOX P28300 1/20 0.38
LOXL2 Q9Y4K0 1/20 0.38
MCHR1 Q99705 2/20 0.34
JAK3 P52333 2/20 0.34
MAP4K3 Q8IVH8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31403617 1.00 FEN1 (0.42) FEN1ALOX5APPDGFRBPDGFRAPIM1
SCHEMBL31508214 0.92 FEN1 (0.39) FEN1ALOX5APPDGFRBPDGFRAPIM1
SCHEMBL32671900 0.92 FEN1 (0.39) FEN1ALOX5APPDGFRBPDGFRAPIM1
SCHEMBL31508259 0.77 EPAS1 (0.35) FEN1ALOX5AP
SCHEMBL2228866 0.76 KDM4E (0.42) PDGFRBPDGFRALOXLOXL2
SCHEMBL16691263 0.72 PDGFRB (0.45) PDGFRBPDGFRAPIM1PIM3PIM2
SCHEMBL16290592 0.72 LOX (0.44) FEN1ALOX5APPDGFRBPDGFRALOX
SCHEMBL1749039 0.72 LOX (0.44) PDGFRBPDGFRALOXLOXL2MCHR1
SCHEMBL31508102 0.72 PARP10 (0.46) FEN1ALOX5APPDGFRBPDGFRAMCHR1
SCHEMBL10255943 0.72 PARP10 (0.46) FEN1ALOX5APPDGFRBPDGFRAMCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025076284-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME DELPHIA THERAPEUTICS, INC. (US) 2025-04-10 WO disclosed