SCHEMBL31403650

SCHEMBL31403650

O=C1CCC(N2Cc3cc(C(=O)Nc4cnc(OC5CCC5)cn4)ccc3C2=O)C(=O)N1

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 10/20 0.56
▸ CSNK1A1 P48729 4/20 0.56
▸ IKZF2 Q9UKS7 12/20 0.47
▸ GSPT1 P15170 1/20 0.43
▸ CYP2C19 P33261 1/20 0.43
▸ KCNH2 Q12809 1/20 0.43
▸ DDB1 Q16531 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31403575 0.89 CRBN (0.56) CRBNCSNK1A1IKZF2GSPT1CYP2C19
SCHEMBL31403590 0.86 CRBN (0.54) CRBNCSNK1A1IKZF2
SCHEMBL31158816 0.80 CRBN (0.61) CRBNCSNK1A1IKZF2GSPT1CYP2C19
SCHEMBL22713505 0.78 CRBN (0.63) CRBNCSNK1A1IKZF2GSPT1DDB1
SCHEMBL31158945 0.77 CRBN (0.82) CRBNCSNK1A1IKZF2GSPT1DDB1
SCHEMBL27387330 0.76 CRBN (0.76) CRBNCSNK1A1IKZF2GSPT1DDB1
SCHEMBL24079598 0.76 CRBN (0.68) CRBNCSNK1A1IKZF2
SCHEMBL23980727 0.76 CRBN (0.67) CRBNCSNK1A1IKZF2GSPT1DDB1
SCHEMBL31158674 0.75 CRBN (0.62) CRBNCSNK1A1IKZF2GSPT1CYP2C19
SCHEMBL24741662 0.75 CRBN (0.61) CRBNCSNK1A1IKZF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025076284-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME DELPHIA THERAPEUTICS, INC. (US) 2025-04-10 — — WO disclosed
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