Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 16/20 | 0.47 |
| ▸ | JAK3 | P52333 | 15/20 | 0.47 |
| ▸ | JAK1 | P23458 | 10/20 | 0.47 |
| ▸ | TYK2 | P29597 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29486783 | 0.76 | PRKCI (0.54) | JAK2JAK3JAK1TYK2ALDH1A1 | |
| SCHEMBL30213789 | 0.76 | PRKCI (0.46) | JAK2JAK3JAK1TYK2ALDH1A1 | |
| SCHEMBL17495401 | 0.76 | PRKCI (0.46) | JAK2JAK3JAK1TYK2ALDH1A1 | |
| SCHEMBL1935167 | 0.76 | PRKCI (0.54) | JAK2JAK3JAK1TYK2ALDH1A1 | |
| SCHEMBL22941677 | 0.76 | JAK2 (0.43) | JAK2JAK3JAK1TYK2ALDH1A1 | |
| SCHEMBL9989736 | 0.75 | JAK2 (0.55) | JAK2JAK3JAK1TYK2CDK2 | |
| SCHEMBL17963822 | 0.72 | JAK2 (0.54) | JAK2JAK3JAK1TYK2ALDH1A1 | |
| SCHEMBL15422239 | 0.72 | JAK2 (0.41) | JAK2JAK3JAK1TYK2ALDH1A1 | |
| SCHEMBL14795009 | 0.72 | JAK2 (0.43) | JAK2JAK3JAK1TYK2ALDH1A1 | |
| SCHEMBL15422006 | 0.71 | IKBKB (0.41) | JAK2JAK3JAK1TYK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076284-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | DELPHIA THERAPEUTICS, INC. (US) | 2025-04-10 | — | — | WO | disclosed |