SCHEMBL31403679

SCHEMBL31403679

COc1ccc2cc(C(=O)Nc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)ccc2c1

nearest known ligand 0.70

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 16/20 0.70
CSNK1A1 P48729 12/20 0.70
IKZF2 Q9UKS7 14/20 0.68
GSPT1 P15170 1/20 0.52
DDB1 Q16531 1/20 0.52
IKZF3 Q9UKT9 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23980468 1.00 CRBN (0.70) CRBNCSNK1A1IKZF2GSPT1DDB1
SCHEMBL23980504 0.92 CRBN (0.69) CRBNCSNK1A1IKZF2GSPT1DDB1
SCHEMBL25627466 0.92 CRBN (0.59) CRBNCSNK1A1IKZF2GSPT1DDB1
SCHEMBL25627459 0.92 CRBN (0.59) CRBNCSNK1A1IKZF2GSPT1DDB1
SCHEMBL32664822 0.91 CRBN (0.65) CRBNCSNK1A1IKZF2GSPT1DDB1
SCHEMBL23980529 0.91 CRBN (0.67) CRBNCSNK1A1IKZF2GSPT1DDB1
SCHEMBL32664820 0.91 CRBN (0.74) CRBNCSNK1A1IKZF2GSPT1DDB1
SCHEMBL23980640 0.90 CRBN (0.64) CRBNCSNK1A1IKZF2
SCHEMBL31403720 0.90 CRBN (0.64) CRBNCSNK1A1IKZF2
SCHEMBL23980628 0.90 CRBN (0.66) CRBNCSNK1A1IKZF2GSPT1DDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025076284-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME DELPHIA THERAPEUTICS, INC. (US) 2025-04-10 WO disclosed