Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.61 |
| ▸ | KLK7 | P49862 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 12/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 5/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | AKT2 | P31751 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 3/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31403778 | 0.93 | MKNK1 (0.62) | MKNK1KLK7DYRK1ACHEK1CHEK2 | |
| SCHEMBL22189861 | 0.78 | MKNK1 (0.77) | MKNK1KLK7DYRK1APRMT5WDR77 | |
| SCHEMBL1054031 | 0.77 | MKNK1 (0.71) | MKNK1KLK7DYRK1APRMT5WDR77 | |
| SCHEMBL16331591 | 0.77 | MKNK1 (0.71) | MKNK1KLK7DYRK1APRMT5WDR77 | |
| SCHEMBL1744648 | 0.77 | MKNK1 (1.00) | MKNK1KLK7DYRK1AFYN | |
| SCHEMBL16331207 | 0.74 | MKNK1 (0.61) | MKNK1KLK7DYRK1APRMT5WDR77 | |
| SCHEMBL16332724 | 0.74 | MKNK1 (0.65) | MKNK1KLK7DYRK1APRMT5WDR77 | |
| SCHEMBL16331312 | 0.71 | MKNK1 (0.61) | MKNK1KLK7DYRK1APRMT5WDR77 | |
| SCHEMBL3357770 | 0.71 | MKNK1 (0.71) | MKNK1KLK7DYRK1APRMT5WDR77 | |
| SCHEMBL16332731 | 0.71 | MKNK1 (0.60) | MKNK1KLK7DYRK1APRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076290-A1 | 5-6-5/6-BISARYL COMPOUNDS AS FLT3 INHIBITORS | PURDUE RESEARCH FOUNDATION (US) | 2025-04-10 | — | — | WO | disclosed |