SCHEMBL31405620

SCHEMBL31405620

CC(C)(C)OC(=O)N1CCN(C(=O)c2cc[nH]c2)CC1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.58
MEN1 O00255 1/20 0.58
ABL1 P00519 1/20 0.49
RIN1 Q13671 1/20 0.49
EPHX2 P34913 2/20 0.48
POLB P06746 1/20 0.48
HDAC4 P56524 1/20 0.47
CRBN Q96SW2 1/20 0.47
CNR2 P34972 1/20 0.46
MAPT P10636 2/20 0.44
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
PTPN2 P17706 1/20 0.44
PTPN1 P18031 1/20 0.44
PTPN6 P29350 1/20 0.44
PARP1 P09874 1/20 0.44
SETD7 Q8WTS6 1/20 0.43
USP2 O75604 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
ATM Q13315 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31133057 0.81 KMT2A (0.59) KMT2AMEN1ABL1RIN1EPHX2
SCHEMBL27468382 0.80 POLB (0.57) KMT2AMEN1EPHX2POLBLMNA
SCHEMBL1374093 0.79 MEN1 (0.68) KMT2AMEN1ABL1RIN1POLB
SCHEMBL8252454 0.79 KMT2A (0.72) KMT2AMEN1ABL1RIN1EPHX2
SCHEMBL3900270 0.78 KMT2A (0.70) KMT2AMEN1ABL1RIN1EPHX2
SCHEMBL2264210 0.78 KMT2A (0.66) KMT2AMEN1ABL1RIN1EPHX2
SCHEMBL29188760 0.78 KMT2A (0.70) KMT2AMEN1ABL1RIN1EPHX2
SCHEMBL3960220 0.78 MEN1 (0.66) KMT2AMEN1ABL1RIN1EPHX2
SCHEMBL5537347 0.78 KMT2A (0.70) KMT2AMEN1ABL1RIN1EPHX2
SCHEMBL1256025 0.77 KMT2A (0.92) KMT2AMEN1ABL1RIN1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775274-A 4-Anilino substituted pyrido [3,2-d ] pyrimidine compound and application thereof 沈阳药科大学 2025-04-08 CN disclosed