Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 13/20 | 0.84 |
| ▸ | RAF1 | P04049 | 11/20 | 0.84 |
| ▸ | CSF1R | P07333 | 11/20 | 0.84 |
| ▸ | DDR2 | Q16832 | 6/20 | 0.84 |
| ▸ | DDR1 | Q08345 | 5/20 | 0.84 |
| ▸ | ARAF | P10398 | 1/20 | 0.71 |
| ▸ | MELK | Q14680 | 2/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | TEK | Q02763 | 1/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | FES | P07332 | 1/20 | 0.40 |
| ▸ | LYN | P07948 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15067359 | 1.00 | BRAF (0.84) | BRAFRAF1CSF1RDDR2DDR1 | |
| SCHEMBL15065801 | 0.93 | BRAF (0.87) | BRAFRAF1CSF1RDDR2DDR1 | |
| SCHEMBL15066865 | 0.93 | BRAF (0.84) | BRAFRAF1CSF1RDDR2DDR1 | |
| SCHEMBL21372404 | 0.92 | BRAF (0.87) | BRAFRAF1CSF1RDDR2DDR1 | |
| SCHEMBL15067385 | 0.92 | BRAF (0.85) | BRAFRAF1CSF1RDDR2DDR1 | |
| SCHEMBL31061586 | 0.91 | BRAF (1.00) | BRAFRAF1CSF1RDDR2DDR1 | |
| SCHEMBL15066024 | 0.91 | BRAF (0.84) | BRAFRAF1CSF1RDDR2DDR1 | |
| SCHEMBL15066998 | 0.91 | BRAF (1.00) | BRAFRAF1CSF1RDDR2DDR1 | |
| SCHEMBL16303091 | 0.91 | BRAF (0.84) | BRAFRAF1CSF1RDDR2DDR1 | |
| SCHEMBL15067512 | 0.91 | BRAF (1.00) | BRAFRAF1CSF1RDDR2DDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3617213-B1 | THIENO[3,2-D]PYRIMIDINE DERIVATIVES HAVING INHIBITORY ACTIVITY FOR PROTEIN KINASES | HANMI PHARMACEUTICAL CO LTD (KR) | 2025-02-19 | — | — | EP | disclosed |