⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12492353 | 0.74 | — | — | |
| SCHEMBL24027203 | 0.74 | — | — | |
| SCHEMBL20495423 | 0.74 | — | — | |
| SCHEMBL14603828 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL30723404 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL28381263 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL28386993 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL12492707 | 0.72 | — | — | |
| SCHEMBL18988381 | 0.67 | — | — | |
| SCHEMBL12133541 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743455-A1 | SARM1 INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025012296-A1 | SARM1 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-16 | — | — | WO | disclosed |