Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.34 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | PTGES | O14684 | 2/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31408562 | 0.92 | SMN1; SMN2 (0.38) | SMN1; SMN2MTNR1AMTNR1BHTTMAPT | |
| SCHEMBL31408302 | 0.90 | SMN1; SMN2 (0.37) | SMN1; SMN2MTNR1AMTNR1BHTTMAPT | |
| SCHEMBL31408249 | 0.87 | SMN1; SMN2 (0.38) | SMN1; SMN2MTNR1AMTNR1BHTTMAPT | |
| SCHEMBL31408395 | 0.87 | SMN1; SMN2 (0.38) | SMN1; SMN2MTNR1AMTNR1BHTTMAPT | |
| SCHEMBL31408570 | 0.86 | SMN1; SMN2 (0.39) | SMN1; SMN2MTNR1AMTNR1BHTTMAPT | |
| SCHEMBL31408394 | 0.84 | SMN1; SMN2 (0.38) | SMN1; SMN2MTNR1AMTNR1BHTTMAPT | |
| SCHEMBL31408403 | 0.84 | SMN1; SMN2 (0.37) | SMN1; SMN2MTNR1AMTNR1BHTTMAPT | |
| SCHEMBL31408457 | 0.84 | SMN1; SMN2 (0.42) | SMN1; SMN2MTNR1AMTNR1BMAPTMEN1 | |
| SCHEMBL31408569 | 0.83 | SMN1; SMN2 (0.39) | SMN1; SMN2MTNR1AMTNR1BMAPTMEN1 | |
| SCHEMBL31408390 | 0.83 | SMN1; SMN2 (0.36) | SMN1; SMN2MTNR1AMTNR1BHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049604-A1 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |