SCHEMBL3140924

SCHEMBL3140924

O=C(NCC1CN(c2ccc(NS(=O)(=O)CCCCl)cc2)C(=O)O1)C1=CC(Cl)=CCC1=S

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3156230 0.85 F10 (0.51) F10
SCHEMBL3151177 0.83 F10 (0.49) F10
SCHEMBL3155927 0.82 F10 (0.60) F10
SCHEMBL3151179 0.82 F10 (0.62) F10
SCHEMBL3155707 0.82 F10 (0.62) F10
SCHEMBL3155650 0.81 F10 (0.65) F10
SCHEMBL3155824 0.81 F10 (0.61) F10
SCHEMBL3150504 0.81 F10 (0.62) F10
SCHEMBL78559 0.80 F10 (1.00) F10
SCHEMBL3150511 0.80 F10 (0.53) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1526132-B1 Substituted oxazolidinone derivatives and their use as factor xa inhibitors BAYER IP GMBH (DE) 2014-03-12 EP disclosed
EP-1411932-B1 SUBSTITUTED OXAZOLIDINONES FOR COMBINATIONAL THERAPY BAYER SCHERING PHARMA AG (DE) 2010-02-10 EP disclosed
EP-1261606-B1 SUBSTITUTED OXAZOLIDINONES AND THEIR USE IN THE FIELD OF BLOOD COAGULATION BAYER HEALTHCARE AG (DE) 2005-02-23 EP disclosed