Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.38 |
| ▸ | GRAMD1A | Q96CP6 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31409362 | 0.90 | HDAC4 (0.43) | HDAC4MAPTESR2NR1H2USP2 | |
| SCHEMBL16217179 | 0.83 | MAPT (0.46) | MAPTESR2NR1H2USP2SMN1; SMN2 | |
| SCHEMBL31409414 | 0.82 | MAPT (0.45) | MAPTESR2NR1H2USP2SMN1; SMN2 | |
| SCHEMBL17327923 | 0.82 | MAPT (0.45) | MAPTESR2NR1H2USP2SMN1; SMN2 | |
| SCHEMBL16220569 | 0.82 | MAPT (0.45) | MAPTESR2NR1H2USP2SMN1; SMN2 | |
| SCHEMBL31409400 | 0.81 | MAPT (0.44) | MAPTESR2NR1H2USP2SMN1; SMN2 | |
| SCHEMBL29222075 | 0.80 | MAPT (0.43) | MAPTESR2NR1H2USP2SMN1; SMN2 | |
| SCHEMBL743031 | 0.80 | MAPT (0.43) | MAPTESR2NR1H2USP2SMN1; SMN2 | |
| SCHEMBL740910 | 0.79 | MAPT (0.44) | MAPTESR2NR1H2USP2SMN1; SMN2 | |
| SCHEMBL16210553 | 0.79 | DPP4 (0.44) | MAPTESR2NR1H2USP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025038920-A1 | HETEROARYL AMINE COMPOUNDS AND USES THEREOF | XENON PHARMACEUTICALS, INC. (CA) | 2025-02-20 | — | — | WO | disclosed |
| WO-2025038917-A1 | HETEROARYL AMINE COMPOUNDS AND USES THEREOF | XENON PHARMACEUTICALS INC. (CA) | 2025-02-20 | — | — | WO | disclosed |