Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | MTR | Q99707 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16850280 | 0.98 | CRBN (0.56) | CRBNPOLBPARP1HTTESR2 | |
| SCHEMBL16850281 | 0.98 | CRBN (0.56) | CRBNPOLBPARP1HTTESR2 | |
| SCHEMBL19022946 | 0.94 | CRBN (0.60) | CRBNESR2PBRM1MTRMAOA | |
| SCHEMBL16850288 | 0.88 | CRBN (0.55) | CRBNESR2PBRM1MTRMAOA | |
| SCHEMBL787539 | 0.88 | CRBN (0.58) | CRBNPOLBPARP1HTTESR2 | |
| SCHEMBL18721459 | 0.87 | CRBN (0.57) | CRBNPARP1PBRM1MTR | |
| SCHEMBL16850272 | 0.87 | CRBN (0.54) | CRBNESR2PBRM1MTRMAOA | |
| SCHEMBL787032 | 0.85 | CRBN (0.49) | CRBNESR2PBRM1MAOAMAOB | |
| SCHEMBL21994815 | 0.83 | CRBN (0.51) | CRBNPARP1PBRM1MTRPARP2 | |
| SCHEMBL25680612 | 0.83 | POLB (0.43) | CRBNPOLBPARP1HTTESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025006553-A1 | METABOTROPIC GLUTAMATE RECEPTOR POSITIVE ALLOSTERIC MODULATORS AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute (US) | 2025-01-02 | — | — | WO | disclosed |