Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL875874 | 0.82 | AURKA (0.34) | AURKAKCNN4KCNA3 | |
| SCHEMBL25296298 | 0.80 | AURKA (0.34) | AURKAKCNN4KCNA3 | |
| SCHEMBL414096 | 0.80 | AURKA (0.34) | AURKAKCNN4KCNA3 | |
| SCHEMBL30228734 | 0.80 | AURKA (0.34) | AURKAKCNN4KCNA3 | |
| SCHEMBL15267008 | 0.79 | LRRK2 (0.34) | — | |
| SCHEMBL24168712 | 0.73 | MAPK1 (0.32) | AURKA | |
| SCHEMBL13834237 | 0.73 | LRRK2 (0.42) | — | |
| SCHEMBL15266283 | 0.71 | CNR1 (0.40) | AURKA | |
| SCHEMBL875535 | 0.70 | LRRK2 (0.38) | — | |
| SCHEMBL13060930 | 0.69 | CYP11B1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025026997-A1 | SUBSTITUED BICYCLIC HETEROCYCLIC YAP-TEAD AND/OR TAZ-TEAD INHIBITORS | MERCK PATENT GMBH (DE) | 2025-02-06 | — | — | WO | disclosed |