SCHEMBL31412995

SCHEMBL31412995

COC=Cc1cc(OCc2ccccc2)c(OC)cc1Br

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.56
ALDH1A1 P00352 2/20 0.56
LMNA P02545 1/20 0.56
HPGD P15428 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
SMPD1 P17405 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
CHRNA7 P36544 2/20 0.43
PTPN1 P18031 3/20 0.43
PDGFRB P09619 1/20 0.43
PDGFRA P16234 1/20 0.43
PTGER4 P35408 1/20 0.43
PTGER2 P43116 1/20 0.43
APP P05067 2/20 0.43
NPC1 O15118 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1318429 0.84 MAPT (0.78) MAPTALDH1A1LMNAHPGDSMN1; SMN2
SCHEMBL6535980 0.84 MAPT (0.78) MAPTALDH1A1LMNAHPGDSMN1; SMN2
SCHEMBL30323788 0.84 MAPT (0.78) MAPTALDH1A1LMNAHPGDSMN1; SMN2
SCHEMBL22555973 0.84 PTGER4 (0.62) MAPTALDH1A1LMNAHPGDSMN1; SMN2
SCHEMBL1318112 0.80 MEN1 (0.56) MAPTALDH1A1LMNAHPGDSMN1; SMN2
SCHEMBL20456326 0.77 MEN1 (0.54) MAPTALDH1A1LMNAHPGDSMN1; SMN2
SCHEMBL20562352 0.77 MEN1 (0.54) MAPTALDH1A1LMNAHPGDSMN1; SMN2
SCHEMBL4596187 0.77 MEN1 (0.54) MAPTALDH1A1LMNAHPGDSMN1; SMN2
SCHEMBL6060097 0.77 APP (0.64) ALDH1A1LMNAHPGDSMN1; SMN2MEN1
SCHEMBL7479264 0.77 APP (0.64) ALDH1A1LMNAHPGDSMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504584-A Dibenzoquinoline compound, preparation method, pharmaceutical composition and application thereof 中国药科大学 2025-02-25 CN disclosed