Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SLC34A1 | Q06495 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 2/20 | 0.36 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30474252 | 1.00 | ESR2 (0.43) | ESR2GPR119NR1H2MAPTSLC34A1 | |
| SCHEMBL30474258 | 0.94 | ESR2 (0.42) | ESR2GPR119NR1H2MAPTSLC34A1 | |
| SCHEMBL31413131 | 0.94 | ESR2 (0.42) | ESR2GPR119NR1H2MAPTSLC34A1 | |
| SCHEMBL30474260 | 0.92 | ESR2 (0.44) | ESR2GPR119NR1H2MAPTSLC34A1 | |
| SCHEMBL30474362 | 0.83 | ESR2 (0.47) | ESR2GPR119NR1H2MAPTSLC34A1 | |
| SCHEMBL31413137 | 0.83 | ESR2 (0.47) | ESR2GPR119NR1H2MAPTSLC34A1 | |
| SCHEMBL30474097 | 0.83 | ESR2 (0.44) | ESR2GPR119NR1H2MAPTSLC34A1 | |
| SCHEMBL31413089 | 0.83 | ESR2 (0.44) | ESR2GPR119NR1H2MAPTSLC34A1 | |
| SCHEMBL30624374 | 0.82 | ESR2 (0.46) | ESR2GPR119NR1H2MAPTSLC34A1 | |
| SCHEMBL31413147 | 0.82 | ESR2 (0.45) | ESR2GPR119NR1H2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119343339-A | Heterocyclic GLP-1 agonists | 加舒布鲁姆生物公司 | 2025-01-21 | — | — | CN | disclosed |