Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 3/20 | 0.32 |
| ▸ | GSK3B | P49841 | 3/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | PRKDC | P78527 | 1/20 | 0.30 |
| ▸ | ATR | Q13535 | 1/20 | 0.30 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27140077 | 1.00 | MAPK8 (0.36) | MAPK8MAPK14OPRL1GSK3AGSK3B | |
| SCHEMBL27141909 | 0.83 | MAPK8 (0.36) | MAPK8MAPK14OPRL1GSK3AGSK3B | |
| SCHEMBL27144673 | 0.83 | MAPK8 (0.36) | MAPK8MAPK14OPRL1GSK3AGSK3B | |
| SCHEMBL27143849 | 0.78 | AOC3 (0.34) | PIK3CAPDE10A | |
| SCHEMBL30718842 | 0.78 | AOC3 (0.34) | PIK3CAPDE10A | |
| SCHEMBL27320416 | 0.76 | MAPK8 (0.36) | MAPK8MAPK14PIK3CAMTOR | |
| SCHEMBL30718808 | 0.73 | MAPK8 (0.36) | MAPK8MAPK14PIK3CAMTORPIK3CB | |
| SCHEMBL27148304 | 0.73 | MAPK8 (0.36) | MAPK8MAPK14PIK3CAMTORPIK3CB | |
| SCHEMBL31390098 | 0.69 | MKNK1 (0.36) | MAPK14 | |
| SCHEMBL26679829 | 0.69 | MKNK1 (0.36) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119325469-A | WEE1 degrading compounds and uses thereof | 百时美施贵宝公司 | 2025-01-17 | — | — | CN | disclosed |