Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27141948 | 1.00 | BACE1 (0.41) | BACE1GRM1ACACBKCNH2HRH3 | |
| SCHEMBL17962757 | 0.93 | BACE1 (0.47) | BACE1ACACBKCNH2SRCPRKD3 | |
| SCHEMBL1161750 | 0.86 | KCNH2 (0.40) | BACE1ACACBKCNH2SRCPRKD3 | |
| SCHEMBL1161752 | 0.86 | KCNH2 (0.40) | BACE1ACACBKCNH2SRCPRKD3 | |
| SCHEMBL29790537 | 0.83 | KCNH2 (0.45) | BACE1KCNH2HRH3SRCL3MBTL1 | |
| SCHEMBL16621259 | 0.83 | KCNH2 (0.45) | BACE1KCNH2HRH3SRCL3MBTL1 | |
| SCHEMBL27139886 | 0.80 | GRM1 (0.37) | BACE1GRM1KCNH2HRH3SRC | |
| SCHEMBL27138895 | 0.80 | SRC (0.39) | GRM1KCNH2HRH3SRCPRKD3 | |
| SCHEMBL16621394 | 0.80 | KCNH2 (0.42) | BACE1KCNH2HRH3L3MBTL1 | |
| SCHEMBL16621393 | 0.80 | KCNH2 (0.42) | BACE1KCNH2HRH3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119325469-A | WEE1 degrading compounds and uses thereof | 百时美施贵宝公司 | 2025-01-17 | — | — | CN | disclosed |