Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 18/20 | 0.57 |
| ▸ | CCNA2 | P20248 | 13/20 | 0.57 |
| ▸ | CCNA1 | P78396 | 13/20 | 0.57 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.56 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.47 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.47 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.47 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.47 |
| ▸ | CDK9 | P50750 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31562196 | 0.83 | CDK2 (0.67) | CDK2CCNE1GSK3B | |
| SCHEMBL31562644 | 0.83 | CDK2 (0.66) | CDK2CCNE1GSK3B | |
| SCHEMBL31562316 | 0.83 | CDK2 (0.66) | CDK2CCNE1GSK3B | |
| SCHEMBL31562440 | 0.83 | CDK2 (0.59) | CDK2CCNE1GSK3B | |
| SCHEMBL31562342 | 0.83 | CDK2 (0.66) | CDK2CCNE1GSK3B | |
| SCHEMBL31503262 | 0.82 | CDK2 (0.54) | CDK2CCNA2CCNA1USP30CCNE1 | |
| SCHEMBL31562568 | 0.82 | CDK2 (0.61) | CDK2CCNE1GSK3B | |
| SCHEMBL31562408 | 0.82 | CDK2 (0.79) | CDK2CCNE1GSK3B | |
| SCHEMBL31562420 | 0.82 | CDK2 (0.67) | CDK2CCNE1GSK3B | |
| SCHEMBL31413677 | 0.82 | CDK2 (0.79) | CDK2CCNE1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025041076-A1 | BICYCLIC COMPOUNDS AS CDK INHIBITORS | BEIGENE SWITZERLAND GMBH (CH) | 2025-02-27 | — | — | WO | disclosed |