Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GRM5 | P41594 | 2/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | PKM | P14618 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31415443 | 1.00 | GAA (0.48) | GAALMNAGRM5FPR2GRM4 | |
| SCHEMBL31231767 | 0.91 | GAA (0.48) | GAALMNAGRM5FPR2GRM4 | |
| SCHEMBL30714528 | 0.91 | GAA (0.48) | GAALMNAGRM5FPR2GRM4 | |
| SCHEMBL26252140 | 0.91 | GAA (0.48) | GAALMNAGRM5FPR2GRM4 | |
| SCHEMBL30599079 | 0.91 | GAA (0.48) | GAALMNAGRM5FPR2GRM4 | |
| SCHEMBL31415270 | 0.88 | GAA (0.49) | GAALMNAGRM5FPR2GRM4 | |
| SCHEMBL31415247 | 0.88 | GAA (0.49) | GAALMNAGRM5FPR2GRM4 | |
| SCHEMBL1839289 | 0.87 | GAA (0.59) | GAALMNAGRM5FPR2GRM4 | |
| SCHEMBL31231772 | 0.87 | GAA (0.59) | GAALMNAGRM5FPR2GRM4 | |
| SCHEMBL31231620 | 0.83 | GAA (0.47) | GAALMNAGRM5FPR2GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054368-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | NICO THERAPEUTICS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |