SCHEMBL31416656

SCHEMBL31416656

FC(F)(F)c1ncc(Br)c(C2CC2)n1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 2/20 0.36
MCHR1 Q99705 1/20 0.34
TMEM97 Q5BJF2 1/20 0.32
CYP17A1 P05093 1/20 0.32
CNR2 P34972 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10220405 0.82 LRRK2 (0.33) CNR2
SCHEMBL31416664 0.79 MALT1 (0.36) MALT1MCHR1TMEM97CYP17A1CNR2
SCHEMBL1759984 0.73 PDE4B (0.40) MCHR1TMEM97
SCHEMBL26738901 0.73 JAK2 (0.33) CNR2
SCHEMBL26608372 0.73 IDH1 (0.33) CNR2
SCHEMBL26616037 0.73 JAK2 (0.33) CNR2
SCHEMBL26738905 0.73 JAK2 (0.33) CNR2
SCHEMBL31689819 0.72 HTT (0.31) MALT1
SCHEMBL31416692 0.72 MALT1 (0.32) MALT1MCHR1TMEM97CYP17A1
SCHEMBL23534336 0.72 GRM4 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025043148-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2025-02-27 WO disclosed