Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | GAA | P10253 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 3/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31417774 | 0.85 | KDM4E (0.36) | KDM4EALDH1A1HSD17B10HPGDHTR4 | |
| SCHEMBL31417569 | 0.85 | KDM4E (0.36) | KDM4EALDH1A1HSD17B10HPGDHTR4 | |
| SCHEMBL31417557 | 0.80 | KDM4E (0.48) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL31417658 | 0.80 | KDM4E (0.48) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL31417790 | 0.80 | KDM4E (0.36) | KDM4EALDH1A1HSD17B10HPGDHTR4 | |
| SCHEMBL29644689 | 0.75 | KDM4E (0.48) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL10320877 | 0.75 | KDM4E (0.48) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL31417731 | 0.75 | KDM4E (0.41) | KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL31417692 | 0.73 | KDM4E (0.37) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL14320278 | 0.72 | KDM4E (0.48) | KDM4EALDH1A1GAAHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025016457-A1 | NEW SUBSTITUTED HETEROCYCLIC COMPOUND AS GSPTS/MYC SIGNAL FLUX REGULATOR | 杭州德睿智药科技有限公司 | 2025-01-23 | — | — | WO | disclosed |