SCHEMBL31419481

SCHEMBL31419481

c1ccc(Nc2cccc3c2c2ccccc2n3-c2ccccc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.53
ATM Q13315 3/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
MEN1 O00255 3/20 0.52
GAA P10253 3/20 0.52
KMT2A Q03164 3/20 0.52
MAPT P10636 3/20 0.52
GLA P06280 1/20 0.52
RECQL P46063 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
ALDH1A1 P00352 3/20 0.47
HPGD P15428 2/20 0.47
ALOX15 P16050 2/20 0.47
TP53 P04637 1/20 0.47
CYP3A4 P08684 1/20 0.47
TSHR P16473 1/20 0.47
CDC25B P30305 1/20 0.47
HSD17B10 Q99714 1/20 0.47
POLB P06746 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16158252 1.00 KDM4E (0.53) KDM4EATML3MBTL1MEN1GAA
SCHEMBL17540402 0.91 KMT2A (0.46) KDM4EATML3MBTL1MEN1GAA
SCHEMBL19660771 0.91 ATM (0.47) KDM4EATML3MBTL1MEN1GAA
SCHEMBL21037624 0.91 ATM (0.47) KDM4EATML3MBTL1MEN1GAA
SCHEMBL18676172 0.90 GAA (0.45) KDM4EATML3MBTL1MEN1GAA
SCHEMBL20904392 0.90 KDM4E (0.46) KDM4EATML3MBTL1MEN1GAA
SCHEMBL29638602 0.90 KDM4E (0.46) KDM4EATML3MBTL1MEN1GAA
SCHEMBL20904394 0.89 AKR1C3 (0.45) KDM4EATML3MBTL1MEN1GAA
SCHEMBL18383769 0.88 KDM4E (0.54) KDM4EATML3MBTL1MEN1GAA
SCHEMBL24416116 0.87 ATM (0.44) KDM4EATML3MBTL1MEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119978007-A Condensed cyclic compound and organic light-emitting device comprising the same 三星显示有限公司 2025-05-13 CN disclosed
CN-111793079-B Condensed cyclic compound and organic light-emitting device comprising the same 三星显示有限公司 2025-02-28 CN disclosed