Choline

Choline

SCHEMBL3142

C[N+](C)(C)CCO

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADORA1ADORA2AADORA2BADORA3GNRHRMPLPDE3APDE3BPDE4APDE4BPDE4CPDE4DPPARASLC5A2

The experimentally established mechanism targets of Choline. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Choline SCHEMBL16558587 1.00
Choline SCHEMBL17629823 1.00 MEN1 (0.92)
Choline SCHEMBL8012313 1.00 MEN1 (0.92)
Choline SCHEMBL14330721 1.00
Choline SCHEMBL13169639 1.00
Choline SCHEMBL27261423 1.00
Choline SCHEMBL29394392 1.00
Choline SCHEMBL300867 1.00 MEN1 (0.92)
Choline SCHEMBL23036016 0.96
Choline SCHEMBL9752221 0.96

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 284309 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260147006-A1 SCREENING METHOD TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2026-05-28 US claimed
US-20260144813-A1 SOLUBLE FIBER COMPOSITIONS TO PREVENT FATTY LIVER AND ALZHEIMER'S CENTRO DE INVESTIGACIÓN Y DE ESTUDIOS AVANZADOS DEL INSTITUTO POLITÉCNICO NACIONAL (MX) 2026-05-28 US claimed
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
EP-4746864-A1 C5 KETONE COMPOSITIONS AND RELATED METHODS FOR TREATING METABOLIC DYSFUNCTION Keto Innovations, LLC (US) 2026-05-27 EP claimed
EP-4747304-A1 DEPOLYMERIZATION PROCESS Repet S.r.l. (IT) 2026-05-27 EP claimed
EP-4748443-A2 SOLID COMPOSITION SUITABLE AS A NUTRITIONAL COMPOSITION OR SUPPLEMENT FOR ANIMALS THAT SUFFER FROM BRAIN RELATED DISORDERS, DECLINE OR DISEASES N.V. Nutricia (NL) 2026-05-27 EP claimed
EP-4401580-B1 SOLID COMPOSITION SUITABLE AS A NUTRITIONAL COMPOSITION OR SUPPLEMENT FOR ANIMALS THAT SUFFER FROM BRAIN RELATED DISORDERS, DECLINE OR DISEASES NUTRICIA NV (NL) 2026-05-27 EP claimed
EP-4746863-A1 ENDOXIFEN COMPOSITIONS AND METHODS OF USE THEREOF AND SYNTHESIS THEREOF Atossa Therapeutics, Inc. (US) 2026-05-27 EP claimed
CN-224271276-U Spiral device of scattering of crystal choline Shandong Aokete Feed Additives Co.,Ltd. (CN) 2026-05-26 CN claimed
US-12636279-B2 Choline salt forms of an HIV capsid inhibitor GILEAD SCIENCES, INC. (US) 2026-05-26 US claimed
US-4059611-A Oxidative process for the preparation of 2-(5H-dibenzo[a,d]cyclohepten-5-on-2-yl)acetic, propionic and butyric acid SYNTEX (U.S.A.) INC. (US) 1977-11-22 US claimed
US-4058122-A Osmotic system with laminated wall formed of different materials ALZA CORPORATION (US) 1977-11-15 US claimed
US-4032578-A HEXADECYL ALCOHOL, BASIC CATALYSTS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1977-06-28 US claimed
US-4029831-A Method of making a multi-gloss panel MASONITE CORPORATION (US) 1977-06-14 US claimed
US-4021447-A SILICA, ALUMINA, ALKALI METAL, WATER, CHOLINE AND PYRROLIDINE MOBIL OIL CORPORATION (US) 1977-05-03 US claimed
US-4005214-A CHOLINE, BACTERICIDE HOFFMANN-LA ROCHE INC. (US) 1977-01-25 US claimed
US-3980679-A Process for the manufacture of glycidyl ethers of monohydric or polyhydric phenols, having improved properties HOECHST AKTIENGESELLSCHAFT (DT) 1976-09-14 US claimed
US-RE28886-E Method for preparing cytidine diphosphate choline KYOWA HAKKO KOGYO CO., LTD. (JA) 1976-06-29 US claimed
US-3947491-A INHIBIT COLOR FORMATION THE PURDUE FREDERICK COMPANY (US) 1976-03-30 US claimed
US-3946115-A GRINDING, EXTRUSION RALSTON PURINA COMPANY (US) 1976-03-23 US claimed