Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 10/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16008355 | 1.00 | NR1H2 (0.42) | NR1H2USP2SMN1; SMN2PIK3CDDDB1 | |
| SCHEMBL2349633 | 0.87 | NR1H2 (0.41) | NR1H2USP2SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL17499881 | 0.87 | NR1H2 (0.50) | NR1H2USP2SMN1; SMN2PIK3CDRORC | |
| SCHEMBL16414857 | 0.86 | HPGD (0.43) | NR1H2USP2SMN1; SMN2DDB1CRBN | |
| SCHEMBL18280935 | 0.86 | HPGD (0.43) | NR1H2USP2SMN1; SMN2DDB1CRBN | |
| SCHEMBL18281007 | 0.86 | HPGD (0.43) | NR1H2USP2SMN1; SMN2DDB1CRBN | |
| SCHEMBL28573624 | 0.85 | NR1H2 (0.42) | NR1H2USP2SMN1; SMN2PIK3CDRORC | |
| SCHEMBL25339655 | 0.84 | NR1H2 (0.41) | NR1H2USP2SMN1; SMN2PIK3CDDDB1 | |
| SCHEMBL25956594 | 0.82 | MEN1 (0.44) | NR1H2USP2SMN1; SMN2PIK3CDRORC | |
| SCHEMBL15719645 | 0.80 | NR1H2 (0.42) | NR1H2USP2SMN1; SMN2PIK3CDDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129021-A1 | SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS | Interdict Bio, Inc. (US) | 2025-04-24 | — | — | US | disclosed |
| WO-2025064718-A1 | SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS | Interdict Bio, Inc. (US) | 2025-03-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250129021-A1 | SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS | MYC, KRAS, NRAS | NR1H2 2741/4885USP2 1781/4885SMN1; SMN2 1576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.