SCHEMBL31421064

SCHEMBL31421064

O=C(NCCc1cn[nH]c1)O[C@@H]1[C@@H](O)CN[C@@H]1Cc1ccc(-c2cncs2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 4/20 0.41
▸ CYP2D6 P10635 3/20 0.41
▸ ALDH1A1 P00352 3/20 0.41
▸ MEN1 O00255 2/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ LMNA P02545 1/20 0.41
▸ MAPK1 P28482 1/20 0.41
▸ HIF1A Q16665 1/20 0.41
▸ CYP2C9 P11712 1/20 0.41
▸ CYP2C19 P33261 1/20 0.41
▸ SLC2A1 P11166 1/20 0.41
▸ ROCK2 O75116 2/20 0.32
▸ GAA P10253 2/20 0.32
▸ WNT1 P04628 1/20 0.32
▸ GSK3B P49841 1/20 0.32
▸ DYRK1A Q13627 1/20 0.32
▸ NAMPT P43490 4/20 0.31
▸ KDM4E B2RXH2 1/20 0.30
▸ TSHR P16473 1/20 0.30
▸ CD38 P28907 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31421111 0.86 CYP2D6 (0.39) SMN1; SMN2CYP2D6ALDH1A1MEN1KMT2A
SCHEMBL31420848 0.85 CYP2D6 (0.43) SMN1; SMN2CYP2D6ALDH1A1MEN1KMT2A
SCHEMBL31421061 0.84 CYP2D6 (0.41) SMN1; SMN2CYP2D6ALDH1A1MEN1KMT2A
SCHEMBL31421200 0.83 CYP2D6 (0.39) SMN1; SMN2CYP2D6ALDH1A1MEN1KMT2A
SCHEMBL31420667 0.83 SMN1; SMN2 (0.61) SMN1; SMN2CYP2D6ALDH1A1MEN1KMT2A
SCHEMBL31420727 0.82 CYP2D6 (0.39) SMN1; SMN2CYP2D6ALDH1A1MEN1KMT2A
SCHEMBL31421079 0.81 SMN1; SMN2 (0.38) SMN1; SMN2CYP2D6ALDH1A1MEN1KMT2A
SCHEMBL31420770 0.81 SMN1; SMN2 (0.38) SMN1; SMN2CYP2D6ALDH1A1MEN1KMT2A
SCHEMBL31420692 0.81 CYP2D6 (0.38) SMN1; SMN2CYP2D6ALDH1A1MEN1KMT2A
SCHEMBL31421141 0.81 CYP2D6 (0.38) SMN1; SMN2CYP2D6ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-04-24 — — US disclosed
WO-2025064718-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS SMN1; SMN2 1576/4885CYP2D6 2401/4885ALDH1A1 2630/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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