SCHEMBL31421278

SCHEMBL31421278

O=C(NCC[C@@H]1CCCN1)O[C@@H]1[C@@H](O)CN[C@@H]1Cc1ccc(-c2ccc(F)c(F)c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ CYP2D6 P10635 3/20 0.40
▸ SMN1; SMN2 Q16637 3/20 0.40
▸ LMNA P02545 1/20 0.40
▸ MAPK1 P28482 1/20 0.40
▸ HIF1A Q16665 1/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ ALDH1A1 P00352 1/20 0.40
▸ CYP2C9 P11712 1/20 0.40
▸ CYP2C19 P33261 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ SLC2A1 P11166 1/20 0.40
▸ HTR2C P28335 1/20 0.33
▸ CHRM3 P20309 1/20 0.33
▸ CTSC P53634 1/20 0.33
▸ MCHR1 Q99705 1/20 0.33
▸ CHRM4 P08173 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31420693 1.00 CYP2D6 (0.40) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL31421023 0.89 CYP2D6 (0.43) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL31420596 0.89 CYP2D6 (0.43) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL31421257 0.89 CYP2D6 (0.44) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL31421083 0.88 CYP2D6 (0.41) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL31420779 0.87 CYP2D6 (0.41) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL31421323 0.87 CYP2D6 (0.41) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL31421484 0.87 CYP2D6 (0.41) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL31420974 0.86 CYP2D6 (0.37) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL31421072 0.86 CYP2D6 (0.37) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-04-24 — — US disclosed
WO-2025064718-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS CYP2D6 2401/4885SMN1; SMN2 1576/4885LMNA 3037/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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