Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19120364 | 0.81 | TSHR (0.62) | TSHRBRD4MAPTMEN1ALDH1A1 | |
| SCHEMBL27412135 | 0.78 | TSHR (0.49) | TSHRBRD4MEN1ALDH1A1KMT2A | |
| SCHEMBL18184521 | 0.76 | TSHR (0.42) | TSHRBRD4PLK1MAPTMEN1 | |
| SCHEMBL17397804 | 0.74 | TSHR (0.41) | TSHRPLK1MAPTTHRBMEN1 | |
| SCHEMBL29438437 | 0.74 | TSHR (0.62) | TSHRPLK1JAK2MEN1ALDH1A1 | |
| SCHEMBL1992513 | 0.74 | GAA (0.44) | TSHRPLK1MAPTTHRBJAK2 | |
| SCHEMBL21621310 | 0.71 | SMN1; SMN2 (0.42) | TSHRPLK1MAPTHPGDSMEN1 | |
| SCHEMBL353369 | 0.70 | DDR1 (0.47) | TSHRALDH1A1CYP1A2METAP2GAA | |
| SCHEMBL23130474 | 0.68 | BRD4 (0.42) | TSHRBRD4MAPTMEN1ALDH1A1 | |
| SCHEMBL21948966 | 0.66 | TSHR (0.61) | TSHRMAPTMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085748-A1 | SMALL MOLECULE INHIBITORS OF KRAS PROTEINS | MERCK SHARP & DOHME LLC (US) | 2025-04-24 | — | — | WO | disclosed |