Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GUSB | P08236 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31273131 | 0.91 | DAO (0.51) | DAOKDM4EGAAGLAALDH1A1 | |
| SCHEMBL31272728 | 0.85 | DAO (0.46) | DAOKDM4EGAAGLAALDH1A1 | |
| SCHEMBL10330638 | 0.82 | KDM4E (0.61) | DAOKDM4EGAAGLAALDH1A1 | |
| SCHEMBL25426199 | 0.81 | MAOB (0.46) | DAOKDM4EGAAGLAALDH1A1 | |
| SCHEMBL30529282 | 0.81 | MAOB (0.46) | DAOKDM4EGAAGLAALDH1A1 | |
| SCHEMBL24373361 | 0.81 | CHEK1 (0.51) | KDM4EGAAGLAALDH1A1HSD17B10 | |
| SCHEMBL25424978 | 0.81 | GAA (0.50) | DAOKDM4EGAAGLAALDH1A1 | |
| SCHEMBL29478893 | 0.81 | CHEK1 (0.51) | KDM4EGAAGLAALDH1A1HSD17B10 | |
| SCHEMBL24373426 | 0.81 | KDM4E (0.59) | KDM4EGAAALDH1A1HSD17B10TSHR | |
| SCHEMBL31423177 | 0.81 | DAO (0.56) | DAOKDM4EGAAGLAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |