SCHEMBL31423409

SCHEMBL31423409

O=C1CCCCCCCCCCCCCC1OC(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.42
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
CA4 P22748 2/20 0.39
KDM4E B2RXH2 3/20 0.37
HSD17B10 Q99714 2/20 0.37
ALDH1A1 P00352 3/20 0.35
POLB P06746 3/20 0.35
MAOA P21397 3/20 0.35
USP2 O75604 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MAOB P27338 1/20 0.31
PKM P14618 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
CA12 O43570 1/20 0.31
CA9 Q16790 1/20 0.31
CA6 P23280 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3959165 0.98 CA1 (0.40) KMT2ACA1CA2CA4KDM4E
SCHEMBL11854691 0.80 KMT2A (0.47) KMT2ACA1CA2CA4KDM4E
SCHEMBL11853006 0.80 KMT2A (0.47) KMT2ACA1CA2CA4KDM4E
SCHEMBL11866853 0.80 KMT2A (0.47) KMT2ACA1CA2CA4KDM4E
SCHEMBL11852548 0.80 KMT2A (0.47) KMT2ACA1CA2CA4KDM4E
SCHEMBL11861011 0.80 KMT2A (0.47) KMT2ACA1CA2CA4KDM4E
SCHEMBL11862412 0.80 KMT2A (0.47) KMT2ACA1CA2CA4KDM4E
SCHEMBL6908639 0.78 CA1 (0.45) KMT2ACA1CA2CA4KDM4E
SCHEMBL22729309 0.75
SCHEMBL20550189 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4495125-A1 A CATALYST FREE SYNTHESIS METHOD FOR INTRODUCING A TRIFLUOROMETHOXY MOIETY INTO AT LEAST ONE ORGANIC COMPOUND Freie Universität Berlin (DE) 2025-01-22 EP disclosed