Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 3/20 | 0.38 |
| ▸ | JAK1 | P23458 | 2/20 | 0.38 |
| ▸ | TYK2 | P29597 | 2/20 | 0.38 |
| ▸ | JAK3 | P52333 | 2/20 | 0.38 |
| ▸ | CDK1 | P06493 | 7/20 | 0.33 |
| ▸ | CDK4 | P11802 | 7/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 7/20 | 0.33 |
| ▸ | CCND1 | P24385 | 7/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.33 |
| ▸ | CDK2 | P24941 | 7/20 | 0.33 |
| ▸ | CCND3 | P30281 | 7/20 | 0.33 |
| ▸ | CDK6 | Q00534 | 7/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.32 |
| ▸ | CDK7 | P50613 | 3/20 | 0.32 |
| ▸ | CDK9 | P50750 | 3/20 | 0.32 |
| ▸ | CCNH | P51946 | 3/20 | 0.32 |
| ▸ | MNAT1 | P51948 | 3/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31423934 | 0.91 | JAK2 (0.36) | JAK2JAK1TYK2JAK3LRRK2 | |
| SCHEMBL31423998 | 0.88 | JAK2 (0.38) | JAK2JAK1TYK2JAK3LRRK2 | |
| SCHEMBL31458686 | 0.87 | JAK2 (0.35) | JAK2JAK1TYK2JAK3CD274 | |
| SCHEMBL31423996 | 0.84 | JAK2 (0.40) | JAK2JAK1TYK2JAK3LRRK2 | |
| SCHEMBL31423897 | 0.84 | JAK2 (0.40) | JAK2JAK1TYK2JAK3LRRK2 | |
| SCHEMBL25673249 | 0.84 | JAK2 (0.38) | JAK2JAK1TYK2JAK3CDK2 | |
| SCHEMBL31160641 | 0.83 | JAK2 (0.38) | JAK2JAK1TYK2JAK3CDK2 | |
| SCHEMBL31423979 | 0.82 | JAK2 (0.37) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL23233965 | 0.81 | JAK2 (0.36) | JAK2JAK1TYK2JAK3CD274 | |
| SCHEMBL31423986 | 0.81 | JAK2 (0.36) | JAK2JAK1TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054386-A1 | CDK2 INHIBITORS AND USES THEREOF | ODYSSEY THERAPEUTICS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |