Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 13/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | HRH2 | P25021 | 1/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.61 |
| ▸ | HTR2C | P28335 | 1/20 | 0.61 |
| ▸ | HRH1 | P35367 | 1/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.61 |
| ▸ | HTR2B | P41595 | 1/20 | 0.61 |
| ▸ | HTR5A | P47898 | 1/20 | 0.61 |
| ▸ | HTR6 | P50406 | 1/20 | 0.61 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.61 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963841 | 1.00 | CASR (0.62) | CASRSIGMAR1HTR1AADRA2BADRA2C | |
| SCHEMBL8175405 | 1.00 | CASR (0.62) | CASRSIGMAR1HTR1AADRA2BADRA2C | |
| SCHEMBL15131017 | 1.00 | CASR (0.62) | CASRSIGMAR1HTR1AADRA2BADRA2C | |
| SCHEMBL7358340 | 0.90 | CASR (0.62) | CASRSIGMAR1HTR1AADRA2BADRA2C | |
| SCHEMBL7964687 | 0.89 | CASR (0.61) | CASRSIGMAR1HTR1AADRA2BADRA2C | |
| SCHEMBL31424069 | 0.89 | CASR (0.61) | CASRSIGMAR1HTR1AADRA2BADRA2C | |
| SCHEMBL15131015 | 0.89 | CASR (0.61) | CASRSIGMAR1HTR1AADRA2BADRA2C | |
| SCHEMBL8163237 | 0.89 | CASR (0.61) | CASRSIGMAR1HTR1AADRA2BADRA2C | |
| SCHEMBL15131194 | 0.88 | CASR (0.71) | CASRSIGMAR1HTR1AADRA2BADRA2C | |
| SCHEMBL6081573 | 0.88 | CASR (0.71) | CASRSIGMAR1HTR1AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054169-A1 | COMPOSITIONS AND METHODS FOR TOPICAL TREATMENT | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2025-03-13 | — | — | WO | disclosed |