Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 7/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | RHEB | Q15382 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31424682 | 1.00 | GRIN1 (0.37) | GRIN1GRIN2BPDE10ATTRPOLB | |
| SCHEMBL31424694 | 0.89 | PDE10A (0.36) | PDE10ABRD4DHODH | |
| SCHEMBL31424637 | 0.88 | BRD4 (0.44) | BRD4 | |
| SCHEMBL31424869 | 0.88 | RHEB (0.42) | GRIN1GRIN2BTTRPOLBALOX15 | |
| SCHEMBL31424670 | 0.88 | SLC6A2 (0.36) | BRD4 | |
| SCHEMBL31424745 | 0.85 | GRIN1 (0.39) | GRIN1GRIN2BDHODH | |
| SCHEMBL31424629 | 0.85 | BRD4 (0.40) | BRD4 | |
| SCHEMBL31424666 | 0.84 | SLC6A4 (0.38) | GRIN1GRIN2BPOLBALOX15NTRK1 | |
| SCHEMBL31424746 | 0.80 | MAPT (0.38) | PDE10A | |
| SCHEMBL31424697 | 0.79 | MAPK1 (0.36) | GRIN1GRIN2BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120020129-A | Substituted nitrogen-containing bicyclic compounds and uses thereof | 广东东阳光药业股份有限公司 | 2025-05-20 | — | — | CN | disclosed |
| CN-119431314-A | Substituted nitrogen-containing bicyclic compounds and uses thereof | 广东东阳光药业股份有限公司 | 2025-02-14 | — | — | CN | disclosed |