SCHEMBL31425762

SCHEMBL31425762

Cn1ccc(CCN=[N+]=[N-])n1

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.40
DDB1 Q16531 1/20 0.35
CRBN Q96SW2 1/20 0.35
KCNH2 Q12809 9/20 0.33
GRIN2B Q13224 1/20 0.33
OPRM1 P35372 1/20 0.33
OPRL1 P41146 1/20 0.33
KMT2A Q03164 1/20 0.32
KEAP1 Q14145 1/20 0.31
NAMPT P43490 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17846282 0.84 KDM4E (0.40) EPHX2DDB1CRBNKCNH2GRIN2B
SCHEMBL30785122 0.72 KDM4E (0.37)
Bromide SCHEMBL28241983 0.69 EPHX2 (0.44) EPHX2DDB1CRBNKCNH2GRIN2B
SCHEMBL15884724 0.68 EPHX2 (0.42) EPHX2DDB1CRBNKCNH2GRIN2B
SCHEMBL20818926 0.68 CYP4F2 (0.43) EPHX2DDB1CRBNKCNH2GRIN2B
SCHEMBL24792887 0.68 EPHX2 (0.42) EPHX2DDB1CRBNKCNH2GRIN2B
SCHEMBL12384367 0.68 EPHX2 (0.42) EPHX2DDB1CRBNKCNH2GRIN2B
SCHEMBL21594259 0.68 CYP2C9 (0.55)
SCHEMBL20818716 0.67 EPHX2 (0.45) EPHX2DDB1CRBNKCNH2GRIN2B
SCHEMBL25646050 0.67 EPHX2 (0.41) EPHX2DDB1CRBNKCNH2GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119552151-A Novel PRMT5 inhibitors and uses thereof 赛岚(杭州)生物医药科技有限公司 2025-03-04 CN disclosed