Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 2/20 | 0.53 |
| ▸ | JAK2 | O60674 | 2/20 | 0.53 |
| ▸ | AXL | P30530 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | FER | P16591 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | MARK3 | P27448 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11970617 | 1.00 | PDPK1 (0.53) | PDPK1JAK2AXLPOLBDYRK1A | |
| SCHEMBL11388 | 0.81 | PDPK1 (0.58) | PDPK1JAK2AXLDYRK1AGSK3B | |
| SCHEMBL13726913 | 0.81 | AXL (0.47) | PDPK1JAK2AXLPOLBGSK3B | |
| SCHEMBL10131351 | 0.81 | POLB (0.46) | PDPK1JAK2POLBDYRK1A | |
| SCHEMBL23087732 | 0.80 | POLB (0.66) | POLBPIM1PIM2PRMT5WDR77 | |
| SCHEMBL28661400 | 0.78 | PDPK1 (0.58) | PDPK1JAK2AXLDYRK1AGSK3B | |
| SCHEMBL27983814 | 0.78 | PDPK1 (0.58) | PDPK1JAK2AXLDYRK1AGSK3B | |
| SCHEMBL17113571 | 0.78 | PDPK1 (0.62) | PDPK1JAK2AXLDYRK1AGSK3B | |
| SCHEMBL1595677 | 0.76 | POLB (0.65) | PDPK1POLBIDO1 | |
| SCHEMBL31491930 | 0.76 | POLB (0.65) | PDPK1POLBIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049994-A1 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | ONCOPIA THERAPEUTICS, INC. D/B/A SK LIFE SCIENCE LABS (US) | 2025-03-06 | — | — | WO | disclosed |