Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 6/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 6/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428808 | 0.95 | PDCD1 (0.49) | PDCD1CD274OPRM1OPRK1MAP4K4 | |
| SCHEMBL31429003 | 0.93 | PDCD1 (0.48) | PDCD1CD274OPRM1OPRK1MAP4K4 | |
| SCHEMBL31428843 | 0.92 | PDCD1 (0.42) | PDCD1CD274OPRM1OPRK1MAPK1 | |
| SCHEMBL31428747 | 0.92 | PDCD1 (0.45) | PDCD1CD274OPRM1OPRK1MAP4K4 | |
| SCHEMBL31428644 | 0.90 | PDCD1 (0.44) | PDCD1CD274OPRM1OPRK1MAP4K4 | |
| SCHEMBL31428415 | 0.89 | PDCD1 (0.41) | PDCD1CD274OPRM1OPRK1ALDH1A1 | |
| SCHEMBL31428726 | 0.89 | PDCD1 (0.43) | PDCD1CD274OPRM1OPRK1MAPK1 | |
| SCHEMBL31428822 | 0.89 | PDCD1 (0.42) | PDCD1CD274OPRM1OPRK1MAP4K4 | |
| SCHEMBL31428622 | 0.88 | PDCD1 (0.44) | PDCD1CD274OPRM1OPRK1MAP4K4 | |
| SCHEMBL31428998 | 0.86 | PDCD1 (0.41) | PDCD1CD274OPRM1OPRK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | BRAF, RAF1, NRAS | PDCD1 1360/4885CD274 1903/4885OPRM1 4177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.