SCHEMBL31430106

CC(C)(C)[Si](C)(C)O[C@H]1[C@@H](OP(=S)(OCCC#N)OCCC#N)[C@H](n2cnc3c(NC(=O)c4ccccc4)ncnc32)O[C@@H]1CO

nearest known ligand 0.46

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	P2RY12	Q9H244	5/20	0.43

▸	ADORA1	P30542	5/20	0.43

▸	PRMT6	Q96LA8	1/20	0.43

▸	DNPH1	O43598	1/20	0.40

▸	ADORA3	P0DMS8	1/20	0.40

▸	ADORA2A	P29274	1/20	0.40

▸	ADORA2B	P29275	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL19250015	0.93	P2RY12 (0.41)	P2RY12ADORA1PRMT6DNPH1
SCHEMBL18927171	0.92	P2RY12 (0.39)	P2RY12ADORA1PRMT6DNPH1
SCHEMBL18917301	0.92	P2RY12 (0.39)	P2RY12ADORA1PRMT6DNPH1
SCHEMBL29749022	0.90	P2RY12 (0.39)	P2RY12ADORA1PRMT6DNPH1
SCHEMBL31430113	0.89	P2RY12 (0.41)	P2RY12PRMT6DNPH1
SCHEMBL19250016	0.89	P2RY12 (0.44)	P2RY12DNPH1
SCHEMBL20022045	0.88	P2RY12 (0.37)	P2RY12ADORA1PRMT6DNPH1
SCHEMBL17860495	0.87	P2RY12 (0.38)	P2RY12ADORA1PRMT6DNPH1
SCHEMBL31430083	0.87	P2RY12 (0.39)	P2RY12PRMT6DNPH1
SCHEMBL22220010	0.86	P2RY12 (0.42)	P2RY12ADORA1PRMT6DNPH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2025054460-A1	PHOSPHODIESTERASE-STABLE ENDO-PHOSPHOROTHIOATE- SUBSTITUTED 2'3'-CGAMP ANALOGUES AS AGONISTS OF STIMULATOR OF INTERFERON GENE	PURDUE RESEARCH FOUNDATION (US)	2025-03-13	—	—	WO	disclosed