Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.39 |
| ▸ | PDE4A | P27815 | 3/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31737736 | 0.75 | PDE4D (0.44) | PDE4DPDE4APDE4BPDE4CKMT2A | |
| SCHEMBL31430773 | 0.74 | PDE4D (0.45) | PDE4DPDE4APDE4BPDE4CKMT2A | |
| SCHEMBL31430866 | 0.73 | MAPT (0.46) | POLBPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL31052554 | 0.69 | LCK (0.41) | POLBKMT2AMEN1MAPT | |
| SCHEMBL25232089 | 0.69 | TYK2 (0.43) | POLBKMT2AALDH1A1TYK2JAK2 | |
| SCHEMBL56989 | 0.69 | ATR (0.46) | POLBKMT2AMEN1ALDH1A1TYK2 | |
| SCHEMBL30227922 | 0.69 | ATR (0.46) | POLBKMT2AMEN1ALDH1A1TYK2 | |
| SCHEMBL31704595 | 0.68 | KDM4E (0.42) | MAPTCHRNA7 | |
| SCHEMBL16135550 | 0.68 | CHRM4 (0.46) | POLBSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL6538150 | 0.68 | KMT2A (0.50) | KMT2ATYK2JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025007784-A1 | HETEROAROMATIC RING COMPOUND, PHARMACEUTICAL COMPOSITION, PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2025-01-09 | — | — | WO | disclosed |