SCHEMBL31432888

SCHEMBL31432888

CC(CC(=O)N1Cc2ccc(Br)cc2C1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.52
▸ DPP8 Q6V1X1 1/20 0.51
▸ DPP9 Q86TI2 1/20 0.51
▸ DPP7 Q9UHL4 1/20 0.51
▸ ALDH1A1 P00352 2/20 0.46
▸ KMT2A Q03164 1/20 0.46
▸ ABHD6 Q9BV23 1/20 0.44
▸ USP19 O94966 4/20 0.43
▸ BCHE P06276 2/20 0.43
▸ NPC1 O15118 1/20 0.43
▸ HPGD P15428 1/20 0.43
▸ TSHR P16473 1/20 0.43
▸ RAB9A P51151 1/20 0.43
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ HSD17B3 P37058 2/20 0.42
▸ USP7 Q93009 1/20 0.41
▸ ACHE P22303 1/20 0.40
▸ NAMPT P43490 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31463256 0.83 DPP7 (0.57) POLBDPP8DPP9DPP7ABHD6
SCHEMBL31432853 0.79 POLB (0.46) POLBALDH1A1USP19
SCHEMBL31432958 0.78 DPP8 (0.62) DPP8DPP9DPP7ALDH1A1ABHD6
SCHEMBL31432838 0.78 DPP8 (0.62) DPP8DPP9DPP7ALDH1A1ABHD6
SCHEMBL31432861 0.76 HSD17B3 (0.48) POLBALDH1A1USP19NPC1HPGD
SCHEMBL30575059 0.74 DPP8 (0.56) DPP8DPP9DPP7ALDH1A1ABHD6
SCHEMBL25258146 0.73 DPP7 (0.66) DPP8DPP9DPP7ABHD6HSD17B3
SCHEMBL8696411 0.73 POLB (0.73) POLBALDH1A1KMT2AUSP19BCHE
SCHEMBL20424518 0.72 DPP8 (0.51) DPP8DPP9DPP7ALDH1A1KMT2A
SCHEMBL20617796 0.72 DPP8 (0.51) DPP8DPP9DPP7KMT2AABHD6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025088073-A1 HETEROCYCLIC COMPOUNDS AS BLT2 AGONISTS AND THEIR MEDICAL USE Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2025-05-01 — — WO disclosed
EP-4545138-A1 HETEROCYCLIC COMPOUNDS AS BLT2 AGONISTS AND THEIR MEDICAL USE Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2025-04-30 — — EP disclosed
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